Amyloidosis
Amyloidosis is a disease that occurs when substances called amyloid proteins build up in your organs. Amyloid is an abnormal protein usually produced by cells in your bone marrow that can be deposited in any tissue or organ. Amyloidosis can affect different organs in different people, and there are many types of amyloid. Amyloidosis frequently affects the heart, kidneys, liver, spleen, nervous system and gastrointestinal tract. Amyloidosis is rare, and the exact cause is often unknown. Treatments are available to help you manage your symptoms of amyloidosis and limit the production of amyloid protein.
Symptomps :
Signs and symptoms of amyloidosis depend on which of your organs are affected. When signs and symptoms are evident, they may include:
- Swelling of your ankles and legs
- Weakness
- Significant weight loss
- Shortness of breath
- Numbness or tingling in your hands or feet
- Diarrhea or constipation
- Feeling full quickly
- Severe fatigue
- An enlarged tongue (macroglossia)
- Skin changes, such as thickening or easy bruising
- Purplish patches (purpura) around the eyes
- An irregular heartbeat
- Difficulty swallowing
- Protein in the urine
When to see a doctor
If you persistently experience any of the signs or symptoms that may be associated with amyloidosis, see your doctor so that he or she can determine whether the underlying cause may be amyloidosis or another problem.

